Scilligence will be presenting and exhibiting at the 256th ACS National Meeting & Expo.

256th ACS National Meeting & Exposition: August 19-23, 2018; Boston Convention & Exhibition Center, Boston, MA (Exhibit Booth #819)
Free Expo Pass:
Registration Link:
https://www.xpressreg.net/services/acssso/redirect.php?showcode=acsf0818&sc=ACSBOS631 
Voucher Code: ACSBOS631
Guest Pass: https://www.xpressreg.net/register/ACSF0818/exhibitor/pdf/pdf.php?o=10069&pb=119666


Presentation: 
Informatics Platform to Facilitate Chemical Education and Knowledge Utilization
Presented by Jinbo Lee, Scilligence
Monday, August 20, 2018, from 10:55 AM – 11:20 AM
Harbor Ballroom III – Westin Boston Waterfront

 

CINF session: Representation of Biologics: Informatics Standards & Challenges

Organizers: David Deng, Scilligence; Claire Bellamy, Pistoia Alliance; and Evan Bolton, NIH
Presiders: David Deng, Scilligence; Claire Bellamy, Pistoia Alliance; and Evan Bolton, NIH

Scilligence Presentation: Current Development and New Challenges of HELM Representation
Presented by David Deng, Scilligence
Monday, August 20, 2018, from 2:00 PM – 2:25 PM
Grand Ballroom E – Westin Boston Waterfront, 425 Summer Street, Boston, MA 02210

Description: As biological molecules are being produced at an accelerated rate every day, a proper registration system (i.e. beyond Excel spreadsheets) needs to be in place. However, the diverse nature of different biological entities creates many challenges for such a system. The lack of industry-wide standards also provides little direction for development. Not-for-profit organizations, like Pistoia Alliance, has been trying to open source previously proprietary standards such as HELM, which has been gaining popularity in peptide and nucleic acid registration. However, there is still a wide range of other entities not covered by these standards. This symposium will focus on current challenges and developments in biologics registration standards.

Related presentation topics include, but not limited to:
1. Challenges and solutions in biologics registration, such as peptide, protein, gene, RNA, DNA, siRNA, plasmid, cell line, antibody, ADC, etc.
2. Current progress and challenges in HELM development.
3. The advantages and disadvantages of open source vs. proprietary.
4. Collaboration within the scientific community in dealing with biologics registration.

Presentations:
– 1:30 PM CINF: Introductory Remarks
– 1:35 PM CINF 71: HELM: Continuing to set the standard for biomolecular representation
– 2:00 PM CINF 72: Current development and new challenges of HELM representation
– 2:25 PM CINF 73: Registering chemically modified oligonucleotides: Implementations and challenges
– 2:50 PM CINF: Intermission
– 3:00 PM CINF 74: Similarity analysis of oligonucleotides based on HELM notation
– 3:25 PM CINF 75: monomer.org: The global hub for (bio)polymer informatics
– 3:50 PM CINF 76: Trials and tribulations of curating peptide and antibody ligands for the IUPHAR/BPS Guide to Pharmacology
– 4:15 PM CINF: Intermission
– 4:25 PM CINF 77: Building a bridge between human-readable and machine-readable representations of biopolymers
– 4:50 PM CINF 78: Bridging the gap between small molecule and biologics editing: Drawing, viewing and sharing complex biomolecules with BioEddie and BiomoleculeToolkit
– 5:15 PM CINF: Concluding Remarks

 

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